Acetylcholin-Rezeptor/en - Versionsgeschichte

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<languages />
Proteine in Zellmembranen mit einer spezifischen Bindungsstelle für den Neurotransmitter Azetylcholin.

Es werden zwei Grundtypen von A. unterschieden : der nikotinerge N-[[Rezeptor]], vorwiegend postsynaptisch am quergestreiften Skelettmuskel, an ganglionären [[Synapse|Synapsen]], am [[Nebennierenmark]], aber auch im [[Zentralnervensystem|ZNS]]. Bei seiner Bindung mit [[Acetylcholin]] wird sein Ionenkanal für Natriumionen geöffnet und durch deren Einstrom die Membran depolarisiert.

Der muskarinerge M-Rezeptor, postsynaptisch an [[Parasympathikus, parasympathisch|parasympathischen]] Nervenendigungen und im ZNS. Bei seiner Aktivierung durch Acetylcholin werden intrazelluläre Botenstoffe (second messenger) gebildet. Am Herzen findet sich der Subtyp M2, dessen Aktivierung durch das vom [[Nervus vagus|Vagusnerven]] freigesetzte Acetylcholin eine Erniedrigung des second messengers [[Cyclisches AMP|cAMP (zyklisches Adenosinmonophosphat)]] bewirkt.

https://de.wikipedia.org/wiki/Acetylcholinrezeptoren <sub>([https://de.wikipedia.org/wiki/Wikipedia:Lizenzbestimmungen_Commons_Attribution-ShareAlike_3.0_Unported Wikipedia CC-by-sa-3.0])</sub>

← Nächstältere Version		Version vom 21. Dezember 2019, 05:33 Uhr
Zeile 6:		Zeile 6:
	The muscarinic M receptor, postsynaptic to [[Parasympathikus,_parasympathisch/en\|parasympathetic]] nerve endings and in the CNS. When activated by acetylcholine, intracellular messengers (second messengers) are formed. At the heart there is the subtype M2, whose activation by the acetylcholine released by the [[Nervus_vagus/en\|vagus nerve]] causes a lowering of the second messenger [[Cyclisches_AMP/en\|cAMP (cyclic adenosine monophosphate)]].		The muscarinic M receptor, postsynaptic to [[Parasympathikus,_parasympathisch/en\|parasympathetic]] nerve endings and in the CNS. When activated by acetylcholine, intracellular messengers (second messengers) are formed. At the heart there is the subtype M2, whose activation by the acetylcholine released by the [[Nervus_vagus/en\|vagus nerve]] causes a lowering of the second messenger [[Cyclisches_AMP/en\|cAMP (cyclic adenosine monophosphate)]].

−	https://de.wikipedia.org/wiki/~~Acetylcholinrezeptoren <sub>([https://de.wikipedia.org/wiki/Wikipedia:Lizenzbestimmungen_Commons_Attribution-ShareAlike_3.0_Unported Wikipedia CC-by-sa-3.0])</sub>~~	+	https://en.wikipedia.org/wiki/Acetylcholine_receptor

@@ Zeile 4: / Zeile 4: @@
 Two basic types of A. are distinguished: the nicotinic N-[[Rezeptor/en|receptor]], predominantly postsynaptic on the striated skeletal muscle, on ganglionary [[Synapse/en|synapses]], on the [[Nebennierenmark/en|adrenal medulla]], but also in the [[Zentralnervensystem/en|CNS]]. When bound with [[Acetylcholin/en|acetylcholine]], its ion channel is opened to sodium ions and the membrane is depolarized by their influx.
-The muscarinic M receptor, postsynaptic to [[parasympathetic, parasympathetic|parasympathetic]] nerve endings and in the CNS. When activated by acetylcholine, intracellular messengers (second messengers) are formed. At the heart there is the subtype M2, whose activation by the acetylcholine released by the [[vagus nerve|vagus nerve]] causes a lowering of the second messenger [[cyclic AMP|cAMP (cyclic adenosine monophosphate)]].
+The muscarinic M receptor, postsynaptic to [[Parasympathikus,_parasympathisch/en|parasympathetic]] nerve endings and in the CNS. When activated by acetylcholine, intracellular messengers (second messengers) are formed. At the heart there is the subtype M2, whose activation by the acetylcholine released by the [[Nervus_vagus/en|vagus nerve]] causes a lowering of the second messenger [[Cyclisches_AMP/en|cAMP (cyclic adenosine monophosphate)]].
 https://de.wikipedia.org/wiki/Acetylcholinrezeptoren <sub>([https://de.wikipedia.org/wiki/Wikipedia:Lizenzbestimmungen_Commons_Attribution-ShareAlike_3.0_Unported Wikipedia CC-by-sa-3.0])</sub>

@@ Zeile 2: / Zeile 2: @@
 Proteins in cell membranes with a specific binding site for the neurotransmitter acetylcholine.
-Two basic types of A. are distinguished: the nicotinic N-[[receptor]], predominantly postsynaptic on the striated skeletal muscle, on ganglionary [[synapse| synapses]], on the [[adrenal medulla]], but also in the [[central nervous system| CNS]]. When bound with [[acetylcholine]], its ion channel is opened to sodium ions and the membrane is depolarized by their influx.
+Two basic types of A. are distinguished: the nicotinic N-[[Rezeptor/en|receptor]], predominantly postsynaptic on the striated skeletal muscle, on ganglionary [[Synapse/en|synapses]], on the [[Nebennierenmark/en|adrenal medulla]], but also in the [[Zentralnervensystem/en|CNS]]. When bound with [[Acetylcholin/en|acetylcholine]], its ion channel is opened to sodium ions and the membrane is depolarized by their influx.
 The muscarinic M receptor, postsynaptic to [[parasympathetic, parasympathetic|parasympathetic]] nerve endings and in the CNS. When activated by acetylcholine, intracellular messengers (second messengers) are formed. At the heart there is the subtype M2, whose activation by the acetylcholine released by the [[vagus nerve|vagus nerve]] causes a lowering of the second messenger [[cyclic AMP|cAMP (cyclic adenosine monophosphate)]].
 https://de.wikipedia.org/wiki/Acetylcholinrezeptoren <sub>([https://de.wikipedia.org/wiki/Wikipedia:Lizenzbestimmungen_Commons_Attribution-ShareAlike_3.0_Unported Wikipedia CC-by-sa-3.0])</sub>

@@ Zeile 4: / Zeile 4: @@
 Two basic types of A. are distinguished: the nicotinic N-[[receptor]], predominantly postsynaptic on the striated skeletal muscle, on ganglionary [[synapse| synapses]], on the [[adrenal medulla]], but also in the [[central nervous system| CNS]]. When bound with [[acetylcholine]], its ion channel is opened to sodium ions and the membrane is depolarized by their influx.
-Der muskarinerge M-Rezeptor, postsynaptisch an [[Parasympathikus, parasympathisch|parasympathischen]] Nervenendigungen und im ZNS. Bei seiner Aktivierung durch Acetylcholin werden intrazelluläre Botenstoffe (second messenger) gebildet. Am Herzen findet sich der Subtyp M2, dessen Aktivierung durch das vom [[Nervus vagus|Vagusnerven]] freigesetzte Acetylcholin eine Erniedrigung des second messengers [[Cyclisches AMP|cAMP (zyklisches Adenosinmonophosphat)]] bewirkt.
+The muscarinic M receptor, postsynaptic to [[parasympathetic, parasympathetic|parasympathetic]] nerve endings and in the CNS. When activated by acetylcholine, intracellular messengers (second messengers) are formed. At the heart there is the subtype M2, whose activation by the acetylcholine released by the [[vagus nerve|vagus nerve]] causes a lowering of the second messenger [[cyclic AMP|cAMP (cyclic adenosine monophosphate)]].
 https://de.wikipedia.org/wiki/Acetylcholinrezeptoren <sub>([https://de.wikipedia.org/wiki/Wikipedia:Lizenzbestimmungen_Commons_Attribution-ShareAlike_3.0_Unported Wikipedia CC-by-sa-3.0])</sub>

@@ Zeile 1: / Zeile 1: @@
 <languages />
-Proteine in Zellmembranen mit einer spezifischen Bindungsstelle für den Neurotransmitter Azetylcholin.
+Proteins in cell membranes with a specific binding site for the neurotransmitter acetylcholine.
 Es werden zwei Grundtypen von A. unterschieden : der nikotinerge N-[[Rezeptor]], vorwiegend postsynaptisch am quergestreiften Skelettmuskel, an ganglionären [[Synapse|Synapsen]], am [[Nebennierenmark]], aber auch im [[Zentralnervensystem|ZNS]]. Bei seiner Bindung mit [[Acetylcholin]] wird sein Ionenkanal für Natriumionen geöffnet und durch deren Einstrom die Membran depolarisiert.