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Reboundphänomen/en: Unterschied zwischen den Versionen

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Bei abruptem Absetzen von Medikamenten kann der vermittelte Effekt durch die stärkere Produktion körpereigener Stoffe ins Gegenteil umschlagen. So steigt der Blutdruck beim schnellen Absetzen von Clonidin und b-Blockern auf die Werte vor Behandlungsbeginn oder sogar darüber hinaus. Deshalb: Therapiebeendigung bei Rebound-verdächtigen Präparaten durch ausschleichendes Absetzen des Medikamentes.
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When drugs are discontinued abruptly, the mediated effect can turn into the opposite due to the increased production of the body's own substances. For example, when clonidine and b-blockers are discontinued rapidly, blood pressure rises to the levels before the start of treatment or even beyond. Therefore: Therapy termination with rebound suspect preparations by slowing down the discontinuation of the drug.

Aktuelle Version vom 16. April 2019, 22:18 Uhr

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When drugs are discontinued abruptly, the mediated effect can turn into the opposite due to the increased production of the body's own substances. For example, when clonidine and b-blockers are discontinued rapidly, blood pressure rises to the levels before the start of treatment or even beyond. Therefore: Therapy termination with rebound suspect preparations by slowing down the discontinuation of the drug.