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The tumor doubling time (TVDT) is the period of time during which the volume of a tumor doubles. The tumor doubling time of a carcinoma, for example, is approximately 2-3 months and determines the aggressiveness of the tumor, among other things. | The tumor doubling time (TVDT) is the period of time during which the volume of a tumor doubles. The tumor doubling time of a carcinoma, for example, is approximately 2-3 months and determines the aggressiveness of the tumor, among other things. | ||
− | + | The doubling time is also decisive for the therapy strategy. The growth of a carcinoma to a diagnostically recognizable tumor size of 1 cm in diameter (approx. one billion cells) requires approx. 30-33 doublings, which corresponds to a period of about 8-9 years (Fig. 11). The tumor doubling time varies greatly and is determined by the number of dividing cells (growth fraction) within the tumor. Tumors with a large growth fraction grow faster than tumors with a small number of dividing cells. | |
https://de.wikipedia.org/wiki/Tumorverdopplungszeit <sub>([https://de.wikipedia.org/wiki/Wikipedia:Lizenzbestimmungen_Commons_Attribution-ShareAlike_3.0_Unported Wikipedia CC-by-sa-3.0])</sub> | https://de.wikipedia.org/wiki/Tumorverdopplungszeit <sub>([https://de.wikipedia.org/wiki/Wikipedia:Lizenzbestimmungen_Commons_Attribution-ShareAlike_3.0_Unported Wikipedia CC-by-sa-3.0])</sub> |
The tumor doubling time (TVDT) is the period of time during which the volume of a tumor doubles. The tumor doubling time of a carcinoma, for example, is approximately 2-3 months and determines the aggressiveness of the tumor, among other things.
The doubling time is also decisive for the therapy strategy. The growth of a carcinoma to a diagnostically recognizable tumor size of 1 cm in diameter (approx. one billion cells) requires approx. 30-33 doublings, which corresponds to a period of about 8-9 years (Fig. 11). The tumor doubling time varies greatly and is determined by the number of dividing cells (growth fraction) within the tumor. Tumors with a large growth fraction grow faster than tumors with a small number of dividing cells.
https://de.wikipedia.org/wiki/Tumorverdopplungszeit (Wikipedia CC-by-sa-3.0)