Array

Translations:Fibrinolyse/1/en: Unterschied zwischen den Versionen

(Auto-translated text.)
 
(Fixed wikilinks.)
 
Zeile 1: Zeile 1:
Fibrinolysis (fibrin cleavage) is the name for the endogenous dissolution of a blood clot ([[thrombus]]) by the enzyme plasmin. Plasmin splits the fibrin polymers, which hold the thrombus together, into small fibrin degradation products, and the thrombus disintegrates. Physiological fibrinolysis in the body is mainly activated by the tissue-specific plasminogen activator and urokinase. The most important non-physiological activators of plasminogen are staphylokinase and streptokinase, which can also be used therapeutically to dissolve thrombi (thrombolysis). Both have in common that they do not have enzymatic activity themselves, but form a complex with plasminogen or plasmin, which is able to activate plasminogen. Today, recombinant (artificially produced) activators (rt-PA, Alteplase) are used therapeutically.
+
Fibrinolysis (fibrin cleavage) is the name for the endogenous dissolution of a blood clot ([[Thrombus/en|thrombus]]) by the enzyme plasmin. Plasmin splits the fibrin polymers, which hold the thrombus together, into small fibrin degradation products, and the thrombus disintegrates. Physiological fibrinolysis in the body is mainly activated by the tissue-specific plasminogen activator and urokinase. The most important non-physiological activators of plasminogen are staphylokinase and streptokinase, which can also be used therapeutically to dissolve thrombi (thrombolysis). Both have in common that they do not have enzymatic activity themselves, but form a complex with plasminogen or plasmin, which is able to activate plasminogen. Today, recombinant (artificially produced) activators (rt-PA, Alteplase) are used therapeutically.

Aktuelle Version vom 22. Mai 2019, 00:24 Uhr

Information zur Nachricht (bearbeiten)
Zu dieser Nachricht ist keine Dokumentation vorhanden. Sofern du weißt, wo und in welchem Zusammenhang sie genutzt wird, kannst du anderen Übersetzern bei ihrer Arbeit helfen, indem du eine Dokumentation hinzufügst.
Nachricht im Original (Fibrinolyse)
Fibrinolyse (Fibrinspaltung) ist die Bezeichnung für die körpereigene Auflösung eines Blutgerinnsels ([[Thrombus]]) durch das Enzym Plasmin. Dabei spaltet Plasmin die Fibrinpolymere, welche den Thrombus zusammen halten, in kleine Fibrinabbauprodukte, und der Thrombus zerfällt. Die physiologische Fibrinolyse wird im Körper hauptsächlich durch den gewebespezifischen Plasminogenaktivator und Urokinase aktiviert. Die wichtigsten nichtphysiologischen Aktivatoren von Plasminogen sind Staphylokinase und Streptokinase, welche auch therapeutisch zur Auflösung von Thromben (Thrombolyse) eingesetzt werden können. Beiden gemeinsam ist, dass sie selbst keine enzymatische Aktivität besitzen, sondern mit Plasminogen oder Plasmin einen Komplex bilden, welcher in der Lage ist, Plasminogen zu aktivieren. Therapeutisch werden heute vor allem rekombinante (künstlich hergestellte) Aktivatoren (rt-PA, Alteplase) genutzt.
ÜbersetzungFibrinolysis (fibrin cleavage) is the name for the endogenous dissolution of a blood clot ([[Thrombus/en|thrombus]]) by the enzyme plasmin. Plasmin splits the fibrin polymers, which hold the thrombus together, into small fibrin degradation products, and the thrombus disintegrates. Physiological fibrinolysis in the body is mainly activated by the tissue-specific plasminogen activator and urokinase. The most important non-physiological activators of plasminogen are staphylokinase and streptokinase, which can also be used therapeutically to dissolve thrombi (thrombolysis). Both have in common that they do not have enzymatic activity themselves, but form a complex with plasminogen or plasmin, which is able to activate plasminogen. Today, recombinant (artificially produced) activators (rt-PA, Alteplase) are used therapeutically.

Fibrinolysis (fibrin cleavage) is the name for the endogenous dissolution of a blood clot (thrombus) by the enzyme plasmin. Plasmin splits the fibrin polymers, which hold the thrombus together, into small fibrin degradation products, and the thrombus disintegrates. Physiological fibrinolysis in the body is mainly activated by the tissue-specific plasminogen activator and urokinase. The most important non-physiological activators of plasminogen are staphylokinase and streptokinase, which can also be used therapeutically to dissolve thrombi (thrombolysis). Both have in common that they do not have enzymatic activity themselves, but form a complex with plasminogen or plasmin, which is able to activate plasminogen. Today, recombinant (artificially produced) activators (rt-PA, Alteplase) are used therapeutically.