Glomeruläre Filtrationsrate, (GFR)/en: Unterschied zwischen den Versionen
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In chronic kidney disease (CKD), five stages are distinguished on the basis of GFR: | In chronic kidney disease (CKD), five stages are distinguished on the basis of GFR: | ||
| − | {| | + | {| | CKD Stadium | GFR| |
| − | | CKD Stadium | ||
| − | | GFR | ||
(ml/min/1,73 m<sup>2</sup>) | (ml/min/1,73 m<sup>2</sup>) | ||
Version vom 16. April 2019, 21:41 Uhr
The GFR is the filtrate volume of all glomeruli per time unit, is 125 ml/min. or 180 l/day.
The GFR depends on the total blood flow of the kidney. A high constancy of blood circulation through an autoregulation system is ensured by changes in mean blood pressure between 85 - 190 mm Hg.
It is determined diagnostically by the clearance of unrestrictedly filtered, non-reabsorbable substances in the glomerulus (e.g. inulin or creatinine).
Chronic kidney disease and GFR:
In chronic kidney disease (CKD), five stages are distinguished on the basis of GFR:
(ml/min/1,73 m2)| Beschreibung | ||
| 1 | > 90 | normale oder erhöhte Nierenfunktion |
| 2 | 60 – 89 | leicht verminderte Nierenfunktion |
| 3a | 45 - 59 | leicht bis mäßig verminderte Nierenfunktion |
| 3b | 30 - 44 | mäßig bis stark verminderte Nierenfunktion |
| 4 | 15 - 29 | stark verminderte Nierenfunktion |
| 5 | < 15 | Nierenversagen (auch als TNI, terminale Niereninsuffizienz bezeichnet) |