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Translations:Intrinsic-System/2/en: Unterschied zwischen den Versionen

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In the complicated, biologically controllable intrinsic system, the rough surface of injured vascular structures first activates the contact labile [[Factor XII]], which acts on the next stage of the system. From here, a cascade-shaped (coagulation cascade or waterfall mechanism; see figure) activation process begins, which leads via [[Factor XI]] and [[Factor IX]] to the activation of [[Factor X|Factor X]]. For the reaction of the latter stage, Ca<sup>2+</sup>, [[factor VIII]]-complex and [[phospholipid]]e from the [[platelets]] are additionally used as co-factors. (platelet factor 3, TF 3) is required. At the stage of joint activation of factor X by the intravascular and extravascular systems, the two reaction pathways merge.
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In the complicated, biologically controllable intrinsic system, the rough surface of injured vascular structures first activates the contact labile [[Faktor_XII/en|Factor XII]], which acts on the next stage of the system. From here, a cascade-shaped (coagulation cascade or waterfall mechanism; see figure) activation process begins, which leads via [[Faktor_XI/en|Factor XI]] and [[Faktor_IX/en|Factor IX]] to the activation of [[Faktor_X/en|Factor X]]. For the reaction of the latter stage, Ca<sup>2+</sup>, [[Faktor_VIII/en|factor VIII]]-complex and [[Phospholipid/en|phospholipid]]e from the [[platelets]] are additionally used as co-factors. (platelet factor 3, TF 3) is required. At the stage of joint activation of factor X by the intravascular and extravascular systems, the two reaction pathways merge.

Aktuelle Version vom 21. Mai 2019, 23:25 Uhr

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Nachricht im Original (Intrinsic-System)
Im komplizierten, biologisch steuerbaren Intrinsic-System wird durch die raue Oberfläche verletzter Gefäßstrukturen zunächst der kontaktlabile [[Faktor XII]] aktiviert, der auf die nächste Stufe des Systems einwirkt. Ab hier beginnt ein kaskadenförmiger (Gerinnungskaskade bzw. Wasserfallmechanismus;siehe Bild) Aktivierungsprozess, der über  [[Faktor XI]] und [[Faktor IX]] zur Aktivierung des [[Faktor X|Faktors X]] führt. Für die Reaktion der letztgenannten Stufe werden als Co-Faktoren zusätzlich noch Ca<sup>2+</sup>, [[Faktor VIII]]-Komplex und [[Phospholipid]]e aus den [[Thrombozyten]] (Plättchenfaktor 3, TF 3) benötigt. Auf der Stufe der gemeinsamen Aktivierung des Faktors X durch das intra- und das extravaskuläre System fließen die beiden Reaktionswege zusammen.
ÜbersetzungIn the complicated, biologically controllable intrinsic system, the rough surface of injured vascular structures first activates the contact labile [[Faktor_XII/en|Factor XII]], which acts on the next stage of the system. From here, a cascade-shaped (coagulation cascade or waterfall mechanism; see figure) activation process begins, which leads via [[Faktor_XI/en|Factor XI]] and [[Faktor_IX/en|Factor IX]] to the activation of [[Faktor_X/en|Factor X]]. For the reaction of the latter stage, Ca<sup>2+</sup>, [[Faktor_VIII/en|factor VIII]]-complex and [[Phospholipid/en|phospholipid]]e from the [[platelets]] are additionally used as co-factors. (platelet factor 3, TF 3) is required. At the stage of joint activation of factor X by the intravascular and extravascular systems, the two reaction pathways merge.

In the complicated, biologically controllable intrinsic system, the rough surface of injured vascular structures first activates the contact labile Factor XII, which acts on the next stage of the system. From here, a cascade-shaped (coagulation cascade or waterfall mechanism; see figure) activation process begins, which leads via Factor XI and Factor IX to the activation of Factor X. For the reaction of the latter stage, Ca2+, factor VIII-complex and phospholipide from the platelets are additionally used as co-factors. (platelet factor 3, TF 3) is required. At the stage of joint activation of factor X by the intravascular and extravascular systems, the two reaction pathways merge.