On the exogenous path, activation takes place very quickly (within seconds), while on the endogenous path, activation takes place over a larger number of intermediate stages and takes longer (minutes). As a rule, both systems are involved in the normal coagulation process. The common final stage of the two activating systems finally makes [[Prothrombin/en|prothrombin]] (factor II) and [[Vitamin_K/en|vitamin K]] formed in the liver is converted into [[Thrombin/en|thrombin]]. The thrombin thus formed is an [[Enzym/en|enzyme]], which also synthesizes the [[Fibrinogen/en|fibrinogen]] (factor I) and thus initiates the formation of [[Fibrin/en|fibrin]].
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Thus, the occlusive plug now obtains its final strength only by contraction of the platelets ''"matted"'' with their pseudopodia among themselves and with the fibrin threads.
Aktuelle Version vom 22. Februar 2022, 12:40 Uhr
Thus, the occlusive plug now obtains its final strength only by contraction of the platelets "matted" with their pseudopodia among themselves and with the fibrin threads.
