Breath regulation

The carbon dioxide partial pressure PaCO₂ and the oxygen partial pressure PaO₂ primarily control respiration. Added to this is the pH of the blood, which respiration uses to stay within vital limits.

Chemoreceptors, nervous stimuli from the lungs, and impulses from the brain help in this process. The blood-brain barrier is permeable to CO₂, thus receptors can measure the partial pressure of carbon dioxide in the cerebrospinal fluid. From there, respiratory rate is controlled, with carbon dioxide having priority over oxygen.

Das heißt, dass unsere Atmung grundsätzlich vor allem durch das CO₂ und weniger durch das O₂ im Blut gesteuert wird.

Only in severe lung diseases the oxygen partial pressure gets a regulating effect, when the PaCO₂ is chronically increased and the respiration has adjusted to it. If then the PaO₂ is decreased, this also triggers a stimulation of respiration.

https://flexikon.doccheck.com/en/Respiration