Translations:Renin-Angiotensin-Aldosteron-System (RAAS)/3/en

At the beginning of the RAAS stands Renin. It is a protease produced mainly in the juxtaglomerular apparatus and there in the epitheloid cells of the vas afferentia. Renin cleaves the peptide angiotensionogen formed in the liver into angiotensin I. This is then converted into highly active angiotensin II by the conversion enzyme (angiotensin converting enzyme; ACE, formed in the pulmonary tract).