Translations:Präklinik/4/en

A drug has to be examined in detail to determine how it behaves in an entire organism. It must be clarified how it is absorbed, distributed, metabolized if necessary and whether and how it is eliminated. Then it has to be clarified whether the drug actually has a healing or soothing effect on the disease. The duration of effectiveness is also measured. It is also necessary to track down any UAWs. A lot of information can only be studied on a whole organism. Since it is not ethically justifiable to test new drugs directly on humans, they are first tested on animals.