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Tumorvaskularisierung/en: Unterschied zwischen den Versionen

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Die Vaskularisierung eines Tumors und der Beginn des invasiven Wachstums mit Durchbrechen der Basalmembran und Eindringen in andere Gewebe, Blutgefäße oder Lymphbahnen liegen zeitlich eng beieinander. Die Durchblutung eines Tumors ist neben dem Wachstum der wichtigste Faktor in der Tumorausbreitung. Das Wachstum eines Tumors wird häufig durch bestimmte Hormone beeinflusst. So besitzen gewisse Tumorzellen (z.B. Mammakarzinomzellen, Endometriumkarzinomzellen u.a.) sog. Hormonrezeptoren, die das Wachstum ebenfalls beeinflussen können. Auf der Blockierung dieser Rezeptoren beruht die Wirkung antihormoneller Therapien (z.B. Antiöstrogentherapie beim Mammakarzinom).
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The vascularization of a tumor and the onset of invasive growth with the breakthrough of the basement membrane and penetration into other tissues, blood vessels or lymphatic pathways are closely related in time. Besides growth, the blood circulation of a tumor is the most important factor in tumor spread. The growth of a tumour is often influenced by certain hormones. Certain tumour cells (e.g. breast carcinoma cells, endometrial carcinoma cells, etc.) possess so-called hormone receptors which can also influence growth. The effect of antihormonal therapies (e.g. antiestrogen therapy for breast cancer) is based on the blocking of these receptors.

Aktuelle Version vom 16. April 2019, 22:32 Uhr

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The vascularization of a tumor and the onset of invasive growth with the breakthrough of the basement membrane and penetration into other tissues, blood vessels or lymphatic pathways are closely related in time. Besides growth, the blood circulation of a tumor is the most important factor in tumor spread. The growth of a tumour is often influenced by certain hormones. Certain tumour cells (e.g. breast carcinoma cells, endometrial carcinoma cells, etc.) possess so-called hormone receptors which can also influence growth. The effect of antihormonal therapies (e.g. antiestrogen therapy for breast cancer) is based on the blocking of these receptors.