The colourless and odourless, crystallizing, water-soluble end product of the protein metabolism in humans and mammals, formed from 2 molecules NH3 (ammonia) of glutamic acid or from the NH2 group of aspartic acid and 1 molecule carbon dioxide (CO2) with the participation of L-ornithine. The excretion takes place through the kidney (12.6-28.6 g/24 h) after complete filtration into the [[glomerulus|glomeruli]] and partial reabsorption into the [[tubulus|tubuli]]; it is reduced in [[renal insufficiency]] and liver diseases, increased with increased protein breakdown. The normal values in the serum are 100-450 mg/l (and reach twice the value in sweat). Urea forms inclusion compounds with inorganic and organic acids [[salt, electrolyte| salts]], with organic substances; has a protein denaturing effect in concentrated solution.
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The colourless and odourless, crystallizing, water-soluble end product of the protein metabolism in humans and mammals, formed from 2 molecules NH3 (ammonia) of glutamic acid or from the NH2 group of aspartic acid and 1 molecule carbon dioxide (CO2) with the participation of L-ornithine. The excretion takes place through the kidney (12.6-28.6 g/24 h) after complete filtration into the [[Glomerulus/en|glomeruli]] and partial reabsorption into the [[tubulus|tubuli]]; it is reduced in [[Niereninsuffizienz/en|renal insufficiency]] and liver diseases, increased with increased protein breakdown. The normal values in the serum are 100-450 mg/l (and reach twice the value in sweat). Urea forms inclusion compounds with inorganic and organic acids [[Salz,_Elektrolyt/en|salts]], with organic substances; has a protein denaturing effect in concentrated solution.
Aktuelle Version vom 22. Mai 2019, 00:25 Uhr
The colourless and odourless, crystallizing, water-soluble end product of the protein metabolism in humans and mammals, formed from 2 molecules NH3 (ammonia) of glutamic acid or from the NH2 group of aspartic acid and 1 molecule carbon dioxide (CO2) with the participation of L-ornithine. The excretion takes place through the kidney (12.6-28.6 g/24 h) after complete filtration into the glomeruli and partial reabsorption into the tubuli; it is reduced in renal insufficiency and liver diseases, increased with increased protein breakdown. The normal values in the serum are 100-450 mg/l (and reach twice the value in sweat). Urea forms inclusion compounds with inorganic and organic acids salts, with organic substances; has a protein denaturing effect in concentrated solution.
