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− | Most important [[Nebenniere/en|adrenal]] | + | Most important [[Nebenniere/en|adrenal]] cortex hormone for the regulation of salt metabolism (mineralocorticoid). |
Its biosynthesis is mediated by the [[Adrenocorticotropes_Hormon/en|adrenocorticotropic hormone]] (ACTH) from the anterior pituitary. Aldosterone stimulates Na<sup>+</sup>-reabsorption and K<sup>+</sup>-secretion in the salt-transporting cells of the kidney and leads to retention of Na<sup>+</sup> and increased excretion of K<sup>+</sup> throughout the body. | Its biosynthesis is mediated by the [[Adrenocorticotropes_Hormon/en|adrenocorticotropic hormone]] (ACTH) from the anterior pituitary. Aldosterone stimulates Na<sup>+</sup>-reabsorption and K<sup>+</sup>-secretion in the salt-transporting cells of the kidney and leads to retention of Na<sup>+</sup> and increased excretion of K<sup>+</sup> throughout the body. |
Most important adrenal cortex hormone for the regulation of salt metabolism (mineralocorticoid).
Its biosynthesis is mediated by the adrenocorticotropic hormone (ACTH) from the anterior pituitary. Aldosterone stimulates Na+-reabsorption and K+-secretion in the salt-transporting cells of the kidney and leads to retention of Na+ and increased excretion of K+ throughout the body.
The secondary result is water retention, and thus an increase in extracellular volume.