Translations:Gerinnungssystem/11/en
Version vom 22. Februar 2022, 13:42 Uhr von Ischler (Diskussion | Beiträge) (Die Seite wurde neu angelegt: „Thus, on the exogenous pathway, activation occurs very rapidly (within seconds), whereas on the endogenous pathway, the activation process proceeds via a large…“)
Thus, on the exogenous pathway, activation occurs very rapidly (within seconds), whereas on the endogenous pathway, the activation process proceeds via a larger number of intermediate steps and requires a longer time (minutes). In the normal coagulation process, both systems are usually involved in an interlocking manner. Through the common final stage of the two activating systems, prothrombin (Factor II) and with the cooperation of vitamin K which is formed in the liver, is converted into thrombin. The resulting thrombin is an enzyme that cleaves the fibrinogen (Factor I), which is also synthesized in the liver, and thus initiates the formation of fibrin.