Main organ for the excretion of water-soluble substances with urine as a glandular product.
The urine then passes through the two Ureteren (ureter) to the bladder and further over the urethra (urethra) from the body.
The filtration performance of the kidney is reduced in diseases of the kidney such as renal insufficiency. Therefore, before administering a drug with renal excretion, it is necessary to know that the performance of the kidney, the glomerular filtration rate, is in the physiological range.
https://de.wikipedia.org/wiki/Niere (Wikipedia CC-by-sa-3.0)