Decrease of Calcitonin Which Promotes Bone Formation

The hormone calcitonin is produced in the thyroid gland and is released in the blood when there is excess calcium - the hormone signal no longer releases calcium from the bone. In this way, calcitonin inhibits, among other things, the osteoclasts that break down bones. Calcitriol is the end product of the D-hormone - formerly called vitamin D. The D-hormone together with thyroid and parathyroid hormones regulates the calcium balance. It is absorbed through food, but our body can also produce it itself. To become effective, the D-hormone must be chemically converted. This happens in the liver and under UV influence in the skin. Then it gets into the kidneys. There it is converted into its final active form calcitriol and released into the blood as an active hormone. Calcitriol works mainly in the intestine and in the kidney itself. In the intestine it promotes the absorption of calcium from food, in the kidneys it prevents the excretion of calcium. Finally, it causes the incorporation of calcium into the bone. The calcium concentration in the blood has a feedback effect. At low concentrations the calcitriol release increases, at high concentrations the calcitriol release decreases.