Fibrin (Latin fibra 'fibre', factor Ia of the blood coagulation cascade) is the activated, cross-linked "adhesive" of human blood coagulation.
It is a protein which is produced by the action of the enzyme thrombin (factor IIa of the coagulation cascade) from the soluble filamentary precursor, the fibrinogen (Factor I of the coagulation cascade). The fibrin polymer is then isotised and forms a net, the blood clot ("white thrombus"), which closes the wound.
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