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− | On the exogenous path, activation takes place very quickly (within seconds), while on the endogenous path, activation takes place over a larger number of intermediate stages and takes longer (minutes). As a rule, both systems are involved in the normal coagulation process. The common final stage of the two activating systems finally makes [[prothrombin]] (factor II) and [[vitamin K]] formed in the liver is converted into [[thrombin]]. The thrombin thus formed is an [[enzyme]], which also synthesizes the [[fibrinogen]] (factor I) and thus initiates the formation of [[fibrin]]. | + | On the exogenous path, activation takes place very quickly (within seconds), while on the endogenous path, activation takes place over a larger number of intermediate stages and takes longer (minutes). As a rule, both systems are involved in the normal coagulation process. The common final stage of the two activating systems finally makes [[Prothrombin/en|prothrombin]] (factor II) and [[Vitamin_K/en|vitamin K]] formed in the liver is converted into [[Thrombin/en|thrombin]]. The thrombin thus formed is an [[Enzym/en|enzyme]], which also synthesizes the [[Fibrinogen/en|fibrinogen]] (factor I) and thus initiates the formation of [[Fibrin/en|fibrin]]. |
On the exogenous path, activation takes place very quickly (within seconds), while on the endogenous path, activation takes place over a larger number of intermediate stages and takes longer (minutes). As a rule, both systems are involved in the normal coagulation process. The common final stage of the two activating systems finally makes prothrombin (factor II) and vitamin K formed in the liver is converted into thrombin. The thrombin thus formed is an enzyme, which also synthesizes the fibrinogen (factor I) and thus initiates the formation of fibrin.